“I’m Matthew. I tried to use alchemy to save my wife Mina from dying from a terminal illness.”
“I’m Kiritsugu, and my wife was a homunculus CONSTRUCTED BY alchemy.”
“Well, unfortunately for ME, the alchemical medicine I gave MY wife made her explode into black sludge.”
“Oh please. I had to sacrifice MY wife as the Vessel of the Holy Grail, and then when I realized that the Grail was evil, I had to strangle an IMAGE OF MY WIFE to death in order to reject it so it wouldn’t destroy the world.”
“Hey guys. Edward Elric here. I’ve got you both beat. I used alchemy to try and resurrect MY DEAD MOTHER, and it cost me an arm and a leg. LITERALLY. Oh yeah, and my little brother lost his ENTIRE BODY.”